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Ribosomal and non-ribosomal PCR targets for the detection of low-density and mixed malaria infections

30 Apr 2019

Abstract excerpt

BACKGROUND: The unexpected high proportion of submicroscopic malaria infections in areas with low transmission intensity challenges the control and elimination of malaria in the Americas. The current PCR-based assays present limitations as most protocols still rely on amplification of few-copies target gene. Here, the hypothesis was that amplification of different plasmodial targets-ribosomal (18S rRNA) and...

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PMID: 31039781
DOI: 10.1186/s12936-019-2781-3

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