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Plasmodium vivax molecular diagnostics in community surveys: pitfalls and solutions

30 Jan 2018

Abstract excerpt

A distinctive feature of Plasmodium vivax infections is the overall low parasite density in peripheral blood. Thus, identifying asymptomatic infected individuals in endemic communities requires diagnostic tests with high sensitivity. The detection limits of molecular diagnostic tests are primarily defined by the volume of blood analysed and by the copy number of the amplified molecular marker serving as the...

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PMID: 29378609
DOI: 10.1186/s12936-018-2201-0

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