Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer

16 Apr 2019

Abstract excerpt

In addition to its implication in hereditary hearing loss, the Gasdermin E (GSDME) gene is also a tumor suppressor involved in cancer progression through programmed cell death. GSDME epigenetic silencing through methylation has been shown in some cancer types, but studies are yet to fully explore its diagnostic/prognostic potential in colorectal cancer on a large-scale. We used public data from The Cancer Genome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30993897
DOI: 10.1002/cam4.2103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancerPMID 30993897Read ↗

Comprehensive analysis, diagnosis, prognosis, and cordycepin (CD) regulations for GSDME expressions in pan-cancersSemantic proximity Read ↗

The Gasdermin E Gene Has Potential as a Pan-Cancer Biomarker, While Discriminating between Different Tumor TypesSemantic proximity Read ↗

Genome-wide Analysis of Aberrant DNA Methylation for Identification of Potential Biomarkers in Colorectal Cancer PatientsSemantic proximity Read ↗

Prognostic and Immunological Role of Gasdermin E in Pan-Cancer AnalysisSemantic proximity Read ↗

An integrative multi-omics framework identifies epigenetic dysregulation of <i>HAND2</i> as a potential primary driver of impaired enteric neural crest cell differentiation in Hirschsprung DiseaseSemantic proximity Read ↗

Genome-wide analysis of DNA methylation in Hirschsprung enteric precursor cells: unraveling the epigenetic landscape of enteric nervous system development.Semantic proximity Read ↗

Genome-wide DNA methylation profiles of low- and high-grade adenoma reveals potential biomarkers for early detection of colorectal carcinomaSemantic proximity Read ↗

DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancersSemantic proximity Read ↗

Developmental genes significantly afflicted by aberrant promoter methylation and somatic mutation predict overall survival of late-stage colorectal cancer.Semantic proximity Read ↗

Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse ModelSemantic proximity Read ↗

Genome-wide methylation analysis shows similar patterns in Barrett’s esophagus and esophageal adenocarcinomaSemantic proximity Read ↗

Methylation of NEUROG1 in Serum Is a Sensitive Marker for the Detection of Early Colorectal CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.