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Article

The Collaborative Cross: A Systems Genetics Resource for Studying Host-Pathogen Interactions.

Cell host & microbe - 10 Apr 2019

Noll Kelsey E, Ferris Martin T, Heise Mark T

Abstract excerpt

Host genetic variation has a major impact on infectious disease susceptibility. The study of pathogen resistance genes, largely aided by mouse models, has significantly advanced our understanding of infectious disease pathogenesis. The Collaborative Cross (CC), a newly developed multi-parental mouse genetic reference population, serves as a tractable model system to study how pathogens interact with genetically...

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Identifiers

PMID: 30974083
DOI: 10.1016/j.chom.2019.03.009
PMCID: PMC6494101

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