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SAMHD1 Enhances Chikungunya and Zika Virus Replication in Human Skin Fibroblasts

5 Apr 2019

Abstract excerpt

Chikungunya virus (CHIKV) and Zika virus (ZIKV) are emerging arboviruses that pose a worldwide threat to human health. Currently, neither vaccine nor antiviral treatment to control their infections is available. As the skin is a major viral entry site for arboviruses in the human host, we determined the global proteomic profile of CHIKV and ZIKV infections in human skin fibroblasts using Stable Isotope Labelling...

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PMID: 30959732
DOI: 10.3390/ijms20071695

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