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The mRNA-bound Proteome of Leishmania mexicana: Novel Genetic Insight into an Ancient Parasite

4 Apr 2019

Abstract excerpt

Leishmania parasite infections, termed the leishmaniases, cause significant global infectious disease burden. The lifecycle of the parasite embodies three main stages that require precise coordination of gene regulation to survive environmental shifts between sandfly and mammalian hosts. Constitutive transcription in kinetoplastid parasites means that gene regulation is overwhelmingly reliant on...

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PMID: 30948621
DOI: 10.1074/mcp.ra118.001307

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