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Article

High metabolic rate and stem cell characteristics of esophageal cancer stem‐like cells depend on the Hsp27–AKT–HK2 pathway

28 Mar 2019

Abstract excerpt

Tumor progression with chemoresistance and local recurrence is commonly happened during treatment of esophageal squamous cell carcinoma (ESCC). Cancer stem cells (CSC) may respond for tumor progression. However, there are few reports regarding metabolism of esophageal CSCs with clinical correlation. In this work, we demonstrated that ESCC cell lines in spheroid culture display CSC phenotypes, including increased...

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PMID: 30920655
DOI: 10.1002/ijc.32301

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