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APELA Expression in Glioma, and Its Association with Patient Survival and Tumor Grade

26 Mar 2019

Abstract excerpt

Glioblastoma (GBM) is the most common and deadliest primary adult brain tumor. Invasion, resistance to therapy, and tumor recurrence in GBM can be attributed in part to brain tumor-initiating cells (BTICs). BTICs isolated from various patient-derived xenografts showed high expression of the poorly characterized Apelin early ligand A (APELA) gene. Although originally considered to be a non-coding gene, the APELA...

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PMID: 30917521
DOI: 10.3390/ph12010045

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