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PAICS is related to glioma grade and can promote glioma growth and migration

26 Jun 2021

Abstract excerpt

Glioma is a common malignant tumour of the brain. In this study, we aimed to investigate diagnostic biomarkers and its role in glioma. Weighted gene co-expression network analysis (WGCNA) and Cytoscape software were used to screen the marker genes in glioma. RT-qPCR and Western blotting methods were performed to determine the expression of PAICS, ERCC1 and XPA genes in glioma tissues. Expression level of PAICS in...

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PMID: 34173716
DOI: 10.1111/jcmm.16647

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