Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines.

Oncotarget - 4 Oct 2016

Palumbo Antonio, Da Costa Nathalia Meireles, De Martino Marco, Sepe Romina, Pellecchia Simona, de Sousa Vanessa Paiva Leite, Nicolau Neto Pedro, Kruel Cleber Dario, Bergman Anke, Nasciutti Luiz Eurico, Fusco Alfredo, Pinto Luis Felipe Ribeiro

Abstract excerpt

The esophageal squamous cell carcinoma (ESCC) is widely known as a highly lethal and poor understood cancer, then requiring the search for novel molecular markers to improve its management and patients survival. Recently, ubiquitin-conjugating enzyme E2C (UBE2C) has been figuring as a prominent tumor biomarker candidate, once it has been recognized as a key player in cell cycle progression. In this way, the aim...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Cell Cycle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Esophageal Neoplasms

Share to Follow-Up Studies

Share to Survival Rate

Share to Tumor Cells, Cultured

Share to Ubiquitin-Conjugating Enzymes

Source

Open in PubMed Open full text

Identifiers

PMID: 27588470
DOI: 10.18632/oncotarget.11674
PMCID: PMC5323199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines.PMID 27588470Read ↗

Ubiquitin-conjugating enzyme 2C (UBE2C) plays as a cancer diagnostic and prognostic marker: A Bioinformatics pan-cancer analysisSemantic proximity Read ↗

UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cellsSemantic proximity Read ↗

Depletion of UBE2C reduces ovarian cancer malignancy and reverses cisplatin resistance via downregulating CDK1Semantic proximity Read ↗

Bioinformatics-based pan-cancer analysis of UBE2CSemantic proximity Read ↗

UBE2S promotes the proliferation and survival of human lung adenocarcinoma cellsSemantic proximity Read ↗

A Comprehensive Bioinformatics Analysis of UBE2C in CancersSemantic proximity Read ↗

Leveraging single-cell and multi-omics approaches to identify MTOR-centered deubiquitination signatures in esophageal cancer therapy.Semantic proximity Read ↗

Review and screening of key genes in esophageal squamous cell carcinomaSemantic proximity Read ↗

Recent Advances From Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma.Semantic proximity Read ↗

Identification of crucial genes associated with esophageal squamous cell carcinoma by gene expression profile analysisSemantic proximity Read ↗

UBE2T silencing suppresses proliferation and induces cell cycle arrest and apoptosis in bladder cancer cellsSemantic proximity Read ↗

Increased expression of UBE2T predicting poor survival of ovarian cancer: based on comprehensive analysis of UBE2s, clinical samples and the GEO databaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.