Viral oncogenesis in cancer: from mechanisms to therapeutics

doi:10.1038/s41392-025-02197-9

Article

Viral oncogenesis in cancer: from mechanisms to therapeutics

11 May 2025

Abstract excerpt

The year 2024 marks the 60th anniversary of the discovery of the Epstein-Barr virus (EBV), the first virus confirmed to cause human cancer. Viral infections significantly contribute to the global cancer burden, with seven known Group 1 oncogenic viruses, including hepatitis B virus (HBV), human papillomavirus (HPV), EBV, Kaposi sarcoma-associated herpesvirus (KSHV), hepatitis C virus (HCV), human T-cell leukemia...

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