Система CRISPR/Cas9, экспрессируемая с плазмиды, подавляет репликацию вируса простого герпеса первого типа в культуре клеток Vero

Abstract excerpt

Herpesviruses are widespread in the human population. Herpes simplex virus type 1 (HSV1) alone infects more than 3.7 billion people. In most of these, the virus establishes a latent form resistant to the action of all antiviral drugs. Moreover, completely drug-resistant strains of herpesviruses are known, which has prompted the search for alternative approaches to the treatment of herpesviruses, including genome...

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