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The N Terminus of Human Cytomegalovirus Glycoprotein O Is Important for Binding to the Cellular Receptor PDGFRα

19 Mar 2019

Abstract excerpt

The human cytomegalovirus is a highly prevalent pathogen that can cause severe disease in immunocompromised hosts. Currently used drugs successfully target the viral replication within the host cell, but their use is restricted due to side effects and the development of resistance. An alternative approach is the inhibition of virus entry, for which understanding the details of the initial virus-cell interaction...

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PMID: 30894468
DOI: 10.1128/jvi.00138-19

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The N Terminus of Human Cytomegalovirus Glycoprotein O Is Important for Binding to the Cellular Receptor PDGFRαPMID 30894468Read ↗

Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry.Semantic proximity Read ↗

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