Article
A Diallel of the Mouse Collaborative Cross Founders Reveals Strong Strain-Specific Maternal Effects on Litter Size.
G3 (Bethesda, Md.) - 7 May 2019
Shorter John R, Maurizio Paul L, Bell Timothy A, Shaw Ginger D, Miller Darla R, Gooch Terry J, Spence Jason S, McMillan Leonard, Valdar William, Pardo-Manuel de Villena Fernando
Abstract excerpt
Reproductive success in the eight founder strains of the Collaborative Cross (CC) was measured using a diallel-mating scheme. Over a 48-month period we generated 4,448 litters, and provided 24,782 weaned pups for use in 16 different published experiments. We identified factors that affect the average litter size in a cross by estimating the overall contribution of parent-of-origin, heterosis, inbred, and...
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