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Prognostic significance of recurring chromosomal abnormalities in transplanted patients with acute myeloid leukemia.

Leukemia - 1 Aug 2019

Canaani Jonathan, Labopin Myriam, Itälä-Remes Maija, Blaise Didier, Socié Gerard, Forcade Edouard, Maertens Johan, Wu Depei, Malladi Ram, Cornelissen Jan J, Huynh Anne, Bourhis Jean Henri, Esteve Jordi, Mohty Mohamad, Nagler Arnon

Abstract excerpt

Baseline cytogenetic studies at diagnosis remain the single most important determinant of outcome in patients with acute myeloid leukemia (AML). However, the prognostic role of the complete gamut of cytogenetic aberrations in AML patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently undefined. In addition, their significance in conjunction with FLT3-ITD status has not...

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PMID: 30846862
DOI: 10.1038/s41375-019-0439-3

Genes

FLT3

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