Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting the NF-κB signaling pathway in chronic tendon disease

27 Feb 2019

Abstract excerpt

Tendon disorders represent the most common musculoskeletal complaint for which patients seek medical attention; inflammation drives tendon degeneration before tearing and impairs healing after repair. Clinical evidence has implicated the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway as a correlate of pain-free return to function after surgical repair. However, it is currently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Nail Diseases and Treatments
Share to Shoulder Injury and Treatment
Share to Tendon Structure and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30814338
DOI: 10.1126/scitranslmed.aav4319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting the NF-κB signaling pathway in chronic tendon diseasePMID 30814338Read ↗

The role of stromal-immune cell interactions in the pathogenesis of tendinopathySemantic proximity Read ↗

Inhibition of IKKβ/NF-κB signaling facilitates tendinopathy healing by rejuvenating inflamm-aging induced tendon-derived stem/progenitor cell senescenceSemantic proximity Read ↗

Nuclear Factor Kappa B Over-Activation in the Intervertebral Disc Leads to Macrophage Recruitment and Severe Disc DegenerationSemantic proximity Read ↗

ERK1/2 drives IL-1β-induced expression of TGF-β1 and BMP-2 in torn tendonsSemantic proximity Read ↗

Regulation of gene expression in human tendinopathy.Semantic proximity Read ↗

Heat Shock Proteins in Tendinopathy: Novel Molecular RegulatorsSemantic proximity Read ↗

HIF1α gates tendon response to overload and drives tendinopathy independently of vascular recruitmentSemantic proximity Read ↗

Integrative single-cell RNA and ATAC sequencing reveals that the FOXO1-PRDX2-TNF axis regulates tendinopathySemantic proximity Read ↗

MicroRNAs Associated with Shoulder Tendon Matrisome Disorganization in Glenohumeral ArthritisSemantic proximity Read ↗

NF-κB Signaling Pathways in Osteoarthritic Cartilage DestructionSemantic proximity Read ↗

Overexpression of mechanical sensitive miR-337-3p alleviates ectopic ossification in rat tendinopathy model via targeting IRS1 and Nox4 of tendon-derived stem cellsSemantic proximity Read ↗

Crucial transcription factors in tendon development and differentiation: their potential for tendon regenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.