Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium.

Genome medicine - 27 Feb 2019

Zoltick Emilie S, Linderman Michael D, McGinniss Molly A, Ramos Erica, Ball Madeleine P, Church George M, Leonard Debra G B, Pereira Stacey, McGuire Amy L, Caskey C Thomas, Sanderson Saskia C, Schadt Eric E, Nielsen Daiva E, Crawford Scott D, Green Robert C

Abstract excerpt

BACKGROUND: Increasing numbers of healthy individuals are undergoing predispositional personal genome sequencing. Here we describe the design and early outcomes of the PeopleSeq Consortium, a multi-cohort collaboration of predispositional genome sequencing projects, which is examining the medical, behavioral, and economic outcomes of returning genomic sequencing information to healthy individuals. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Health Knowledge, Attitudes, Practice

Share to Motivation

Share to Precision Medicine

Share to Surveys and Questionnaires

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 30808425
DOI: 10.1186/s13073-019-0619-9
PMCID: PMC6391825

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium.PMID 30808425Read ↗

Elective genomic sequencing for adults in research, clinical and commercial contextsSemantic proximity Read ↗

Personal Genome Sequencing in Ostensibly Healthy Individuals and the PeopleSeq ConsortiumSemantic proximity Read ↗

The NextGen Study: patient motivation for participation in genome sequencing for carrier statusSemantic proximity Read ↗

Psychological and behavioural impact of returning personal results from whole-genome sequencing: the HealthSeq project.Semantic proximity Read ↗

Attitudes of nearly 7000 health professionals, genomic researchers and publics toward the return of incidental results from sequencing researchSemantic proximity Read ↗

Care delivery considerations for widespread and equitable implementation of inherited cancer predisposition testing.Semantic proximity Read ↗

Impact of Receiving Secondary Results from Genomic Research: A 12‐Month Longitudinal StudySemantic proximity Read ↗

Population Genomic Screening for Hereditary Cancer Risk: Patient Experience, Perceptions, and Downstream Clinical Outcomes.Semantic proximity Read ↗

Ethical and Psychosocial Issues Associated with Genetic Testing for Hereditary Tumor Predisposition SyndromesSemantic proximity Read ↗

Informed consent for exome sequencing research in families with genetic disease: The emerging issue of incidental findingsSemantic proximity Read ↗

Decision-making, attitudes, and understanding among patients and relatives invited to undergo genome sequencing in the 100,000 Genomes Project: A multisite survey studySemantic proximity Read ↗

Design of a randomized controlled trial for genomic carrier screening in healthy patients seeking preconception genetic testingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.