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Development of a Novel Loop-Mediated Isothermal Amplification Method to Detect Guiana Extended-Spectrum (GES) β-Lactamase Genes in Pseudomonas aeruginosa

4 Feb 2019

Abstract excerpt

Infections caused by multidrug-resistant Pseudomonas aeruginosa in hospitalised patients are often fatal, and nosocomial infections caused by Guiana extended-spectrum (GES) β-lactamase-producing strains are of growing concern. Several genotypes of the GES β-lactamase gene (blaGES) include a single missense mutation, a change from G to A at nucleotide position 493 (G493A) that changes glycine to serine; the mutant...

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PMID: 30778337
DOI: 10.3389/fmicb.2019.00025

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