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Dual role of TGF-β in early pregnancy: clues from tumor progression

17 Feb 2019

Abstract excerpt

TGF-β signaling in the endometrium is active during the implantation period and has a pivotal role in regulating endometrial receptivity and embryo implantation. During embryo implantation, both apoptosis and proliferation of endometrial cells happen at the same time and it seems TGF-β is the factor that controls both of these processes. As shown in cancer cells, in special conditions this cytokine can have a...

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PMID: 30772900
DOI: 10.1093/biolre/ioz024

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