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Real microgravity condition promoted regeneration capacity of induced pluripotent stem cells during the TZ‐1 space mission

6 Feb 2019

Abstract excerpt

Induced pluripotent stem cells (iPSCs) are reprogrammed somatic cells that gained self-renewal and differentiation capacity similar to embryonic stem cells. Taking the precious opportunity of the TianZhou-1 spacecraft mission, we studied the effect of space microgravity (µg) on the self-renewal capacity of iPSCs. Murine iPSCs carrying pluripotency reporter Oct4-GFP were used. The Oct4-EGFP-iPSCs clones were...

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PMID: 30724402
DOI: 10.1111/cpr.12574

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