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Article

CD28H expression identifies resident memory CD8 + T cells with less cytotoxicity in human peripheral tissues and cancers

5 Nov 2018

Abstract excerpt

The CD28H/B7-H5 pathway is a newly identified pathway of the B7 family. In human peripheral blood, the receptor CD28H is preferentially expressed on naïve T cells and repetitive stimulation of T cells leads to the loss of CD28H expression. Here we examined the expression of the CD28H/B7-H5 pathway in human peripheral tissues, as well as in human cancers. We found that CD28H is preferentially expressed on T cells...

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PMID: 30713797
DOI: 10.1080/2162402x.2018.1538440

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