Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of DNA Repair Genes via Homologous Recombination (HR) in Ovarian Cancer

2 Feb 2019

Abstract excerpt

Ovarian cancer is one of the most common types of cancer in women. The repair system via homologous recombination repairs double-strand breaks (DSB) of DNA, which are the most mortal for cell, out of all DNA damages. The genes, which encode the double-strand break repairing proteins, are highly polymorphic and, taking into account the significance of the repaired defects for cancer development, it seems important...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to DNA Repair Mechanisms
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30712190
DOI: 10.1007/s12253-019-00604-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of DNA Repair Genes via Homologous Recombination (HR) in Ovarian CancerPMID 30712190Read ↗

Association between single nucleotide polymorphisms (SNPs) of XRCC2 and XRCC3 homologous recombination repair genes and ovarian cancer in Polish women.Semantic proximity Read ↗

Association between RAD51, XRCC2 and XRCC3 gene polymorphisms and risk of ovarian cancer: a case control and an in silico study.Semantic proximity Read ↗

Polymorphisms in DNA repair genes and epithelial ovarian cancer risk.Semantic proximity Read ↗

Homologous recombination deficiency in ovarian cancer: a review of its epidemiology and managementSemantic proximity Read ↗

DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy OutcomeSemantic proximity Read ↗

Ovarian cancer: Status of homologous recombination pathway as a predictor of drug responseSemantic proximity Read ↗

Homologous recombination inquiry through ovarian malignancy investigations: JGOG3025 StudySemantic proximity Read ↗

Homologous Recombination Inquiry Through Ovarian Malignancy Investigations: The Japanese Gynecologic Oncology Group study JGOG3025Semantic proximity Read ↗

The clinical pathological characteristics and prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients：A Retrospective Cohort StudySemantic proximity Read ↗

Role of DNA repair and cell cycle control genes in ovarian cancer susceptibility.Semantic proximity Read ↗

DNA Damage Response Alterations in Ovarian Cancer: From Molecular Mechanisms to Therapeutic OpportunitiesSemantic proximity Read ↗

Germline and somatic mutations of homologous recombination-associated genes in Japanese ovarian cancer patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.