Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Micro RNA ‐let‐7c suppresses hepatitis C virus replication by targeting Bach1 for induction of haem oxygenase‐1 expression

1 Feb 2019

Abstract excerpt

MicroRNAs are small noncoding RNAs that are central factors between hepatitis C virus (HCV) and host cellular factors for viral replication and liver disease progression, including liver fibrosis, cirrhosis and hepatocellular carcinoma. In the present study, we found that overexpressing miR-let-7c markedly reduced HCV replication because it induced haem oxygenase-1 (HO-1) expression by targeting HO-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C virus research
Share to MicroRNA in disease regulation
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30706605
DOI: 10.1111/jvh.13072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Micro RNA ‐let‐7c suppresses hepatitis C virus replication by targeting Bach1 for induction of haem oxygenase‐1 expressionPMID 30706605Read ↗

The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes.Semantic proximity Read ↗

MicroRNAs: Role in hepatitis C virus pathogenesisSemantic proximity Read ↗

Cellular microRNA networks regulate host dependency of hepatitis C virus infectionSemantic proximity Read ↗

Hepatitis B virus mRNAs functionally sequester let-7a and enhance hepatocellular carcinomaSemantic proximity Read ↗

Differentially expressed microRNAs in Huh-7 cells expressing HCV core genotypes 3a or 1b: potential functions and downstream pathways.Semantic proximity Read ↗

Hepatitis C Virus-Induced Changes in MicroRNA 107 (miRNA-107) and miRNA-449a Modulate CCL2 by Targeting the Interleukin-6 Receptor Complex in HepatitisSemantic proximity Read ↗

MicroRNA Expression Profiling in HCV-Infected Human Hepatoma Cells Identifies Potential Anti-Viral Targets Induced by Interferon-αSemantic proximity Read ↗

Let-7b is a novel regulator of hepatitis C virus replicationSemantic proximity Read ↗

Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virusSemantic proximity Read ↗

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus InfectionSemantic proximity Read ↗

Hepatitis C Virus-Mediated Enhancement of MicroRNA miR-373 Impairs the JAK/STAT Signaling PathwaySemantic proximity Read ↗

A Long Noncoding RNA Regulates Hepatitis C Virus Infection Through Interferon Alpha–Inducible Protein 6Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.