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Article

Genotoxic effects of silver nanoparticles with/without coating in human liver HepG2 cells and in mice

31 Jan 2019

Abstract excerpt

With the rapid expansion of human exposure to silver nanoparticles (AgNPs), the genotoxicity screening is critical to the biosafety evaluation of nanosilver. This study assessed DNA damage and chromosomal aberration in the human hepatoma cell line (HepG2) as well as the effects on the micronucleus of bone marrow in mice induced by 20 nm polyvinylpyrrolidone-coated nanosilver (PVP-AgNPs) and 20 nm bare nanosilver...

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PMID: 30701584
DOI: 10.1002/jat.3779

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