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Article

Factors affecting the in vitro micronucleus assay for evaluation of nanomaterials.

Mutagenesis - 1 Jan 2017

Li Yan, Doak Shareen H, Yan Jian, Chen David H, Zhou Min, Mittelstaedt Roberta A, Chen Ying, Li Chun, Chen Tao

Abstract excerpt

A number of in vitro methodologies have been used to assess the genotoxicity of different nanomaterials, including titanium dioxide nanoparticles (TiO2 NPs) and silver nanoparticles (AgNPs). The in vitro micronucleus assay is one of the most commonly used test methods for genotoxicity evaluation of nanomaterials. However, due to the novel features of nanomaterials, such as high adsorption capacity and...

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PMID: 27567283
DOI: 10.1093/mutage/gew040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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