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Clinical factors associated with circulating tumor <scp>DNA</scp> (ct<scp>DNA</scp>) in primary breast cancer

24 Jan 2019

Abstract excerpt

Noninvasive circulating tumor DNA (ct DNA ) can be used to predict breast cancer recurrence and prognosis. In this study, we detected 226 and 114 somatic variants in tumor DNA from 70 primary breast cancer ( PBC ) patients (98.59%) and ct DNA from 48 patients (67.61%), respectively. Gene frequencies of tumor DNA and ct DNA significantly correlated ( R 2 = 0.9532, P < 0.0001), and tumor‐derived variants were...

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PMID: 30672098
DOI: 10.1002/1878-0261.12456

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