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Recurrent PDGFRB mutations in unicentric Castleman disease

3 Jan 2019

Abstract excerpt

Castleman disease (CD) is a rare heterogeneous group of lymphoproliferative disorders that share common lymph node histopathological features [ 1 , 2 ]. It can be classified into unicentric CD (UCD), HHV-8-positive multicentric CD (MCD) and HHV-8-negative MCD (also called idiopathic MCD or iMCD) according to the number of swollen lymph nodes, Kaposi sarcoma-associated herpesvirus/human herpesvirus-8 (HHV-8)...

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PMID: 30607019
DOI: 10.1038/s41375-018-0323-6

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