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Association between MEG3/miR-181b polymorphisms and risk of ischemic stroke

1 Dec 2018

Abstract excerpt

BACKGROUND: Recent evidence suggests that long non-coding RNAs (lncRNAs) are key regulators in the pathological process of ischemic stroke (IS). Maternally expressed gene 3 (MEG3) was observed to be up-regulated in IS, acting as a competing endogenous RNA for miR-181b to regulate ischemic brain injury. The purpose of this study was to evaluate the association of tagSNPs in MEG3 (i.e., rs7158663 and rs4081134) and...

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PMID: 30579356
DOI: 10.1186/s12944-018-0941-z

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