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Autophagy, cancer stem cells and drug resistance

20 Dec 2018

Abstract excerpt

Autophagy is a cellular survival mechanism that is induced by cancer therapy, among other stresses, and frequently contributes to cancer cell survival during long periods of dormancy and the eventual outgrowth of metastatic disease. Autophagy degrades large cellular structures that, once broken down, contribute to cellular survival through the recycling of their constituent metabolites. However, the extent to...

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PMID: 30570140
DOI: 10.1002/path.5222

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