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Article

microRNA-2110 functions as an onco-suppressor in neuroblastoma by directly targeting Tsukushi

14 Dec 2018

Abstract excerpt

microRNA-2110 (miR-2110) was previously identified as inducing neurite outgrowth in a neuroblastoma cell lines BE(2)-C, suggesting its differentiation-inducing and oncosuppressive function in neuroblastoma. In this study, we demonstrated that synthetic miR-2110 mimic had a generic effect on reducing cell survival in neuroblastoma cell lines with distinct genetic backgrounds, although the induction of cell...

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PMID: 30550571
DOI: 10.1371/journal.pone.0208777

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