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Article

Post-GWAS in prostate cancer: from genetic association to biological contribution.

Nature reviews. Cancer - 1 Jan 2019

Farashi Samaneh, Kryza Thomas, Clements Judith, Batra Jyotsna

Abstract excerpt

Genome-wide association studies (GWAS) have been successful in deciphering the genetic component of predisposition to many human complex diseases including prostate cancer. Germline variants identified by GWAS progressively unravelled the substantial knowledge gap concerning prostate cancer heritability. With the beginning of the post-GWAS era, more and more studies reveal that, in addition to their value as risk...

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PMID: 30538273
DOI: 10.1038/s41568-018-0087-3

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