Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High expression of TFEB is associated with aggressive clinical features in colorectal cancer

1 Nov 2018

Abstract excerpt

OBJECTIVES: The transcription factor EB (TFEB), a member of the micropthalmia family, has been found to be associated with autophagy and upregulated in some kinds of tumors. However, very few studies focused on TFEB in colorectal cancer (CRC). TFEB expression status and its relevance to clinical features in CRC would be analyzed in this study. MATERIALS AND METHODS: Real-time PCR, Western blot, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Kruppel-like factors research
Share to NF-κB Signaling Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30519051
DOI: 10.2147/ott.s180112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High expression of TFEB is associated with aggressive clinical features in colorectal cancerPMID 30519051Read ↗

Dysregulation of Transcription Factor EB Contributes to Cell Proliferation, Metastasis and Stemness in Breast CancerSemantic proximity Read ↗

Transcription Factor EBF1 Over-Expression Suppresses Tumor Growth in vivo and in vitro via Modulation of the PNO1/p53 Pathway in Colorectal CancerSemantic proximity Read ↗

TFEB Signalling-Related MicroRNAs and AutophagySemantic proximity Read ↗

Protein interactions of FAM134B with EB1 and APC/beta‐catenin in vitro in colon carcinomaSemantic proximity Read ↗

TCF12 Protein Functions as Transcriptional Repressor of E-cadherin, and Its Overexpression Is Correlated with Metastasis of Colorectal CancerSemantic proximity Read ↗

HLF transactivates TFEB to promote gallbladder cancer stem cells’ self-renewal and determines tumor response to distinct therapiesSemantic proximity Read ↗

The autophagy-independent role of BECN1 in colorectal cancer metastasis through regulating STAT3 signaling pathway activationSemantic proximity Read ↗

Increased Expression of ATG10 in Colorectal Cancer Is Associated with Lymphovascular Invasion and Lymph Node MetastasisSemantic proximity Read ↗

FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axisSemantic proximity Read ↗

Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer CellsSemantic proximity Read ↗

Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.Semantic proximity Read ↗

YY1 cooperates with TFEB to regulate autophagy and lysosomal biogenesis in melanomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.