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Detection in Italy of a porcine Enterococcus faecium isolate carrying the novel phenicol-oxazolidinone-tetracycline resistance gene poxtA

14 Nov 2018

Abstract excerpt

Sir, Acquired resistance to linezolid in staphylococci and enterococci emerged shortly after its introduction into clinical practice. Initially, resistance mechanisms mediated by mutations affecting the ribosomal target were reported.1 Subsequently, transferable linezolid resistance determinants have emerged, including the cfr gene, encoding a 23S rRNA methylase,2 and the optrA gene, encoding a ribosomal...

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PMID: 30517691
DOI: 10.1093/jac/dky505

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Related research

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Research trail→

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Detection in Italy of a porcine Enterococcus faecium isolate carrying the novel phenicol-oxazolidinone-tetracycline resistance gene poxtAPMID 30517691Read ↗

Detection of the phenicol–oxazolidinone–tetracycline resistance gene poxtA in Enterococcus faecium and Enterococcus faecalis of food-producing animal origin in ChinaSemantic proximity Read ↗

Detection of Oxazolidinone Resistance Genes and Characterization of Genetic Environments in Enterococci of Swine Origin, ItalySemantic proximity Read ↗

Characterization of poxtA, a novel phenicol–oxazolidinone–tetracycline resistance gene from an MRSA of clinical originSemantic proximity Read ↗

Detection of the Phenicol–Oxazolidinone Resistance Gene poxtA in Enterococcus faecium and Enterococcus faecalis from Food-Producing Animals during 2008–2018 in KoreaSemantic proximity Read ↗

Linezolid-resistant (Tn6246::fexB-poxtA) Enterococcus faecium strains colonizing humans and bovines on different continents: similarity without epidemiological linkSemantic proximity Read ↗

Genetic features of the poxtA linezolid resistance gene in human enterococci from FranceSemantic proximity Read ↗

A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal originSemantic proximity Read ↗

Antimicrobial Susceptibility of Enterococcus Isolates from Cattle and Pigs in Portugal: Linezolid Resistance Genes optrA and poxtASemantic proximity Read ↗

Transferable Resistance Gene optrA in Enterococcus faecalis from Swine in BrazilSemantic proximity Read ↗

Characterization of oxazolidinone and phenicol resistance genes in non-clinical enterococcal isolates from KoreaSemantic proximity Read ↗

Coexistence of the Oxazolidinone Resistance–Associated Genes cfr and optrA in Enterococcus faecalis From a Healthy Piglet in BrazilSemantic proximity Read ↗

Persistence of transferable oxazolidinone resistance genes in enterococcal isolates from a swine farm in ChinaSemantic proximity Read ↗

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