Detection of the phenicol–oxazolidinone–tetracycline resistance gene poxtA in Enterococcus faecium and Enterococcus faecalis of food-producing animal origin in China

Abstract excerpt

Sir, Oxazolidinones, including linezolid and tedizolid, are effective antimicrobial agents for treating infections caused by MDR Gram-positive bacteria, including VRE.1,2 Linezolid is the first commercially available oxazolidinone that can inhibit protein synthesis by binding to the peptidyltransferase centre of the bacterial 23S rRNA. After introduction of linezolid, the resistance mechanism that emerged rapidly...

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