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Article

Identification of a novel mutation in APP gene in a Thai subject with early-onset Alzheimer's disease

1 Nov 2018

Abstract excerpt

Introduction: Early-onset Alzheimer’s disease (AD) accounts for than less 1% of all AD cases, with large variation in the reported genetic contributions of known dementia genes. Mutations in the amyloid precursor protein ( APP ) gene were the first to be recognized as the cause of AD. Methods: Here, a male patient with probable early-onset AD at the age of 55 years from Thailand was investigated by...

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PMID: 30510423
DOI: 10.2147/ndt.s180174

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