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Genome mining reveals uncommon alkylpyrones as type III PKS products from myxobacteria

1 Dec 2018

Abstract excerpt

Type III polyketide synthases (PKSs) are comparatively small homodimeric enzymes affording natural products with diverse structures and functions. While type III PKS biosynthetic pathways have been studied thoroughly in plants, their counterparts from bacteria and fungi are to date scarcely characterized. This gap is exemplified by myxobacteria from which no type III PKS-derived small molecule has previously been...

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PMID: 30506464
DOI: 10.1007/s10295-018-2105-6

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