Article
Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines
1 Nov 2018
Abstract excerpt
To improve our understanding of ovarian cancer, we performed genome-wide analyses of 45 ovarian cancer cell lines. Given the challenges of genomic analyses of tumors without matched normal samples, we developed approaches for detection of somatic sequence and structural changes and integrated these with epigenetic and expression alterations. Alterations not previously implicated in ovarian cancer included...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.