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Article

Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands

19 Nov 2018

Abstract excerpt

Abstract Measles causes a transient immune suppression, leading to increased susceptibility to opportunistic infections. In experimentally infected non-human primates (NHPs) measles virus (MV) infects and depletes pre-existing memory lymphocytes, causing immune amnesia. A measles outbreak in the Dutch Orthodox Protestant community provided a unique opportunity to study the pathogenesis of measles immune...

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PMID: 30470742
DOI: 10.1038/s41467-018-07515-0

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