Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of Oxidative Stress Effects on Senescence Patterning of Human Adult and Perinatal Tissue-Derived Stem Cells in Short and Long-term Cultures

1 Jan 2018

Abstract excerpt

Human Mesenchymal Stem Cells (hMSCs) undergo senescence in lifespan. In most clinical trials, hMSCs experience long-term expansion ex vivo to increase cell number prior to transplantation, which unfortunately leads to cell senescence, hampering post-transplant outcomes. Hydrogen peroxide (H 2 O 2 ) in vitro represents a rapid, time and cost-effective tool, commonly used as oxidative stress tantalizing the stem...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Pluripotent Stem Cells Research
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30443170
DOI: 10.7150/ijms.27181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of Oxidative Stress Effects on Senescence Patterning of Human Adult and Perinatal Tissue-Derived Stem Cells in Short and Long-term CulturesPMID 30443170Read ↗

Changes in mesenchymal stem cells following long-term culture in vitroSemantic proximity Read ↗

Oxidative stress induces senescence in human mesenchymal stem cellsSemantic proximity Read ↗

Effects of Oxidative Stress on Mesenchymal Stem Cell BiologySemantic proximity Read ↗

Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based TherapySemantic proximity Read ↗

H 2 O 2 Accumulation Mediates Differentiation Capacity Alteration, But Not Proliferative Decline, in Senescent Human Fetal Mesenchymal Stem CellsSemantic proximity Read ↗

Inducing Oxidative Stress-Driven Senescent Phenotype in Induced Pluripotent Stem Cell Derived Cardiomyocytes.Semantic proximity Read ↗

How to track cellular aging of mesenchymal stromal cells?Semantic proximity Read ↗

Human dermal fibroblast senescence in response to single and recurring oxidative stressSemantic proximity Read ↗

N-acetylcysteine protects induced pluripotent stem cells from in vitro stress: impact on differentiation outcomeSemantic proximity Read ↗

Proteomic and metabolomic analysis of H2O2-induced premature senescent human mesenchymal stem cellsSemantic proximity Read ↗

Probable impact of age and hypoxia on proliferation and microRNA expression profile of bone marrow-derived human mesenchymal stem cellsSemantic proximity Read ↗

Epigenetic Alterations under Oxidative Stress in Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.