Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysregulated gene expression predicts tumor aggressiveness in African-American prostate cancer patients

30 Oct 2018

Abstract excerpt

Molecular mechanisms underlying the health disparity of prostate cancer (PCa) have not been fully determined. In this study, we applied bioinformatic approach to identify and validate dysregulated genes associated with tumor aggressiveness in African American (AA) compared to Caucasian American (CA) men with PCa. We retrieved and analyzed microarray data from 619 PCa patients, 412 AA and 207 CA, and we validated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cancer-related molecular mechanisms research
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30397274
DOI: 10.1038/s41598-018-34637-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysregulated gene expression predicts tumor aggressiveness in African-American prostate cancer patientsPMID 30397274Read ↗

Genes Associated with Prostate Cancer Are Differentially Expressed in African American and European American MenSemantic proximity Read ↗

Genomic, epigenomic, and transcriptomic signatures of prostate cancer between African American and European American patientsSemantic proximity Read ↗

Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancerSemantic proximity Read ↗

Epigenome‐wide association study of prostate cancer in African American men identified differentially methylated genesSemantic proximity Read ↗

Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian menSemantic proximity Read ↗

MNX1 Is Oncogenically Upregulated in African-American Prostate CancerSemantic proximity Read ↗

Copy number and gene expression differences between African American and Caucasian American prostate cancerSemantic proximity Read ↗

MicroRNA-regulated transcriptome analysis identifies four major subtypes with prognostic and therapeutic implications in prostate cancerSemantic proximity Read ↗

Elucidation of the Genomic-Epigenomic Interaction Landscape of Aggressive Prostate Cancer.Semantic proximity Read ↗

Identification of Differentially Methylated Genes in Normal Prostate Tissues from African American and Caucasian MenSemantic proximity Read ↗

Expression differences between African American and Caucasian prostate cancer tissue reveals that stroma is the site of aggressive changesSemantic proximity Read ↗

Minireview: the molecular and genomic basis for prostate cancer health disparities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.