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Article

Effect of natural products on the production and activity of Clostridium difficile toxins in vitro

18 Oct 2018

Abstract excerpt

Clostridium difficile infection is a toxin-mediated disease of the colon. C. difficile virulence is primarily attributed to the production of toxin A and toxin B; thus this study was aimed to investigate the effect of a range of natural products on the production and activity of C. difficile toxins in vitro. Twenty-two natural products were investigated against four C. difficile strains. The activity of products...

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PMID: 30356168
DOI: 10.1038/s41598-018-33954-2

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