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Hog1 Regulates Stress Tolerance and Virulence in the Emerging Fungal Pathogen Candida auris

23 Oct 2018

Abstract excerpt

The rapid global emergence and resistance of Candida auris to current antifungal drugs highlight the importance of understanding the virulence traits exploited by this human fungal pathogen to cause disease. Here, we characterize the stress resistance profile of C. auris and the role of the Hog1 stress-activated protein kinase (SAPK) in stress resistance and virulence. Our findings that C. auris is acutely...

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PMID: 30355673
DOI: 10.1128/msphere.00506-18

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