Energy Constraint as a Novel Mechanism Linking Exercise and Health

Abstract excerpt

Humans and other species adapt dynamically to changes in daily physical activity, maintaining total energy expenditure within a narrow range. Chronic exercise thus suppresses other physiological activity, including immunity, reproduction, and stress response. This exercise-induced downregulation improves health at moderate levels of physical activity but can be detrimental at extreme workloads.

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• Share to Adipose Tissue and Metabolism
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• Share to Obesity, Physical Activity, Diet