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Article

A newly generated neuronal cell model of CLN7 disease reveals aberrant lysosome motility and impaired cell survival

1 Oct 2018

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Share to Adenosine and Purinergic Signaling
Share to Calcium signaling and nucleotide metabolism
Share to Lysosomal Storage Disorders Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30301600
DOI: 10.1016/j.ymgme.2018.09.009

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A newly generated neuronal cell model of CLN7 disease reveals aberrant lysosome motility and impaired cell survivalPMID 30301600Read ↗

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Loss of the lysosomal protein CLN3 modifies the lipid content of the nuclear envelope leading to DNA damage and activation of YAP1 pro-apoptotic signalingSemantic proximity Read ↗

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