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Article

Defining an optimal time window to screen for hepatoblastoma in children with Beckwith‐Wiedemann syndrome

30 Sept 2018

Abstract excerpt

Patients with Beckwith-Wiedemann spectrum (BWSp) undergo quarterly alpha-fetoprotein measurement for hepatoblastoma (HB) screening up to 4 years of age, paralleling the epidemiology of nonsyndromic HB. However, specific data on the timing of HB development in BWSp are lacking. Here we compare the timing of presentation of HBs in BWSp with a control cohort of consecutive HB cases, demonstrating that halving...

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PMID: 30270492
DOI: 10.1002/pbc.27492

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