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Article

DNA Repair Proteins as Therapeutic Targets in Ovarian Cancer

14 Sept 2018

Abstract excerpt

Epithelial ovarian cancer is a serious public health problem worldwide with the highest mortality rate of all gynecologic cancers. The current standard-of-care for the treatment of ovarian cancer is based on chemotherapy based on adjuvant cisplatin/carboplatin and taxane regimens that represent the first-line agents for patients with advanced disease. The DNA repair activity of cancer cells determines the...

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PMID: 30215333
DOI: 10.2174/1389203719666180914091537

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