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Article

Gut microbiota, cognitive frailty and dementia in older individuals: a systematic review.

Clinical interventions in aging - 1 Jan 2018

Ticinesi Andrea, Tana Claudio, Nouvenne Antonio, Prati Beatrice, Lauretani Fulvio, Meschi Tiziana

Abstract excerpt

Cognitive frailty, defined as the coexistence of mild cognitive impairment symptoms and physical frailty phenotype in older persons, is increasingly considered the main geriatric condition predisposing to dementia. Recent studies have demonstrated that gut microbiota may be involved in frailty physiopathology by promoting chronic inflammation and anabolic resistance. The contribution of gut microbiota to the...

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Identifiers

PMID: 30214170
DOI: 10.2147/CIA.S139163
PMCID: PMC6120508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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