Article
Novel biomarker profiles in experimental aged maternal mice with hypertensive disorders of pregnancy.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jan 2019
Furuya Kiichiro, Kumasawa Keiichi, Nakamura Hitomi, Nishimori Katsuhiko, Kimura Tadashi
Abstract excerpt
Recently, advanced maternal age (AMA) has increased in Western countries because of late marriage and advances in assisted reproductive technology. One major complication of AMA is hypertensive disorders of pregnancy (HDP). While clinical investigations into human AMA have been reported, there has been limited information obtained from basic research. In this investigation, we established the AMA mouse model...
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