Article
Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis.
Addiction (Abingdon, England) - 1 Feb 2019
Skaaby Tea, Kilpeläinen Tuomas O, Taylor Amy E, Mahendran Yuvaraj, Wong Andrew, Ahluwalia Tarunveer S, Paternoster Lavinia, Trompet Stella, Stott David J, Flexeder Claudia, Zhou Ang, Brusselle Guy, Sajjad Ayesha, Lahousse Lies, Tiemeier Henning, Have Christian Theil, Thuesen Betina H, Kårhus Line Lund, Møllehave Line Tang, Leth-Møller Katja Biering, Shabanzadeh Daniel Mønsted, Gonzalez-Quintela Arturo, Power Chris, Hyppönen Elina, Kuh Diana, Hardy Rebecca, Meitinger Thomas, Jukema J Wouter, Völker Uwe, Nauck Matthias, Völzke Henry, Friedrich Nele, Bonten Tobias N, Noordam Raymond, Mook-Kanamori Dennis O, Tolstrup Janne S, Taube Christian, Peters Annette, Grallert Harald, Strauch Konstantin, Schulz Holger, Grarup Niels, Hansen Torben, Pedersen Oluf, Burgess Stephen, Munafò Marcus R, Linneberg Allan
Abstract excerpt
AIMS: To use the rs1229984 variant associated with alcohol consumption as an instrument for alcohol consumption to test the causality of the association of alcohol consumption with hay fever, asthma, allergic sensitization and serum total immunoglobulin (Ig)E. DESIGN: Observational and Mendelian randomization analyses using genetic variants as unbiased markers of exposure to estimate causal effects, subject to...
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