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Article

Increased H. pylori stool shedding and EPIYA-D cagA alleles are associated with gastric cancer in an East Asian hospital.

PloS one - 1 Jan 2018

Talarico Sarah, Leverich Christina K, Wei Bing, Ma Jie, Cao XinGuang, Guo YongJun, Han GuangSen, Yao Lena, Self Steve, Zhao Yuzhou, Salama Nina R

Abstract excerpt

BACKGROUND: Helicobacter pylori infection increases risk for gastric cancer. Geographic variation in gastric cancer risk has been attributed to variation in carriage and type of the H. pylori oncogene cagA. Colonization density may also influence disease and cagA has been associated with higher shedding in stool. However, the relationship between H. pylori load in the stool and in the stomach is not clear....

Topics

Adult
Aged
Alleles
Amino Acid Sequence
Antigens, Bacterial
Bacterial Proteins
China
Feces
Female
Helicobacter pylori
Hospitals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Middle Aged

Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 30208068
DOI: 10.1371/journal.pone.0202925
PMCID: PMC6135355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-30208068-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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